Journal Articles

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Browsing Journal Articles by Author "Mwebaze, N.,"

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    Aerobic-exercise training effects on immunological markers in individuals on highly active antiretroviral therapy in Uganda
    (Nurtekin ERKMEN, 2024-06-30) Mwebaze, N.,; Nsibambi, C. A. N.,; Ojuka, E.,; Maghanga, M.,
    There is critical relevance in understanding the multidisciplinary management of HIV/AIDs among individuals obtaining health services in Uganda. The purpose of the study was therefore to assess the effects of aerobic exercise training on immunological markers as a clinical outcome of Human Immunodeficiency Virus positive clients attending a chronic HIV clinic at a General Military HospitalBombo. A pre-post experimental design was used to understand differences between the experimental and control groups. Participants were Human Immunodeficiency Virus positive clients who had been on treatment that is, Highly Active Antiretroviral Therapy for at least 12 months. They were randomly assigned to either a control group (Group 1): who did not participate in the aerobic exercise, or an experimental group (Group 2): where a 12-week moderate intensity aerobic exercise, for not less than 3 times a week, and for at least 45 minutes per session was administered. Both groups were assessed using a physical activity readiness questionnaire. Thereafter, assessment of the clinical outcomes that is, immunological measures using Clusters of differentiation 4 were assessed. While the experimental group participated in the exercise, the control group members were followed up during the 12 weeks to ensure that they remained in the study. After the 12 weeks post-test was done. The findings of this study revealed that aerobic exercises significantly increased Clusters of differentiation 4 count in both males and females by 29.7% on average (p<0.001). Aerobic exercise is therefore likely to increase quality of life, reduce mobility and mortality rates in Human Immunodeficiency Virus positive clients on highly active antiretroviral therapy.
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    Implications of a twelve-week aerobic exercise on functional work capacity in HIV positive clients on antiretroviral therapy
    (Nurtekin ERKMEN, 2024-08-01) Mwebaze, N.,; Nsibambi, C. A. N.,; Ojuka, E.,; Maghanga, M.
    The implications of aerobic exercise on functional work capacity of Human Immunodeficiency Virus (HIV) positive clients on antiretroviral therapy (ART) in Uganda have been established. ART and the efforts to scale it up have significantly improved the value of life and life’s hope of among PLHIV. Despite the presence of ART HIV disease is still seen in wards and a significant loss of life due to AIDS. This study provides useful information to the Ministry of Health of Uganda on the implications of aerobic exercises on functional work capacity as a clinical outcome to HIV positive clients in Uganda. This helps in refining the existing information on aerobic exercises and their relevancy in management of HIV positive clients. An experimental study was conducted among HIV positive clients who had been on treatment for at least 12 months prior to the study. Volunteers were randomly assigned to a control group (Group 1), where no treatment was administered, and an experimental group (Group 2), where a twelve-week moderate intensity aerobic exercise was administered. Assessment of functional work capacity was done as a pre-test and post-test for both groups. The results showed that aerobic exercises significantly improved both heart rate and VO2max with p-values of <0.001 indicating a significant improvement of VO2max from 25.13 to 34.19ml/kg/min while the control group improved by 3.73ml/kg/min. Aerobic exercise can, therefore, improve the quality of life; reduce the cost of management, mobility and mortality rates in HIV positive clients on ART in Uganda.