Department of Chemistry

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Browsing Department of Chemistry by Author "Akampurira, D."

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    Isolated compounds from Kigelia africana stem bark extract against Mycobacterium tuberculosis: Insights into In-silico studies
    (Royal Society of Chemistry, 2026-06-25) Onen, Patrick; Achiro,M.; Nanyonga,S.K.; Akampurira, D.; Tumwesigye R.; Ocira, D.; Otema, T.; Gumula, I.
    In this present study, we aimed to; 1.Isolate, characterize and elucidate the structures 2.Carryout In-silico analyses to investigate the potential anti- mycobacterial activity of known compounds isolated from K. africana stem bark against key M. tuberculosis, Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus) targets.
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    Transformation of agricultural waste into nutraceutical and pharmaceutical products with the aid of In-silico methods
    (Royal Society of Chemistry, 2026-06-25) Tumwesigye, R.; Akello, R.O.; Akampurira, D.; Asiimire, B.; Kikonyogo, I.
    This project transforms Ugandan agricultural waste, such as pineapple and soursop residues, into valuable nutraceuticals and pharmaceuticals. By combining green chemistry, LC-MS/MS & GC-MS/MS analysis with in-silico molecular docking and toxicity profiling, we identify bioactive compounds with high therapeutic potential. This sustainable, circular model provides a scalable, cost-effective framework for drug discovery, offering an affordable approach to health innovation that aligns with global sustainability goals.