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dc.contributor.authorStubbs, B.
dc.contributor.authorVancampfort, D.
dc.contributor.authorVeronese, N.
dc.contributor.authorKahl, K. G.
dc.contributor.authorMitchell, A. J.
dc.contributor.authorLin, P.-Y.
dc.contributor.authorTseng, P.-T.
dc.contributor.authorMugisha, J.
dc.contributor.authorSolmi, M.
dc.contributor.authorCarvalho, A. F.
dc.contributor.authorKoyanagi, A.
dc.date.accessioned2022-01-19T06:54:33Z
dc.date.available2022-01-19T06:54:33Z
dc.date.issued2017-04-04
dc.identifier.citationStubbs, B... et al (2017). Depression and physical health multimorbidity: Primary data and country-wide meta-analysis of population data from 190 593 people across 43 low- and middle-income countries. Psychological Medicine, 47(12), 2107-2117. doi:10.1017/S0033291717000551.en_US
dc.identifier.uriDOI: https://doi.org/10.1017/S0033291717000551
dc.identifier.urihttps://kyuspace.kyu.ac.ug/xmlui/handle/20.500.12504/248
dc.description.abstractDespite the known heightened risk and burden of various somatic diseases in people with depression, very little is known about physical health multimorbidity (i.e. two or more physical health co-morbidities) in individuals with depression. This study explored physical health multimorbidity in people with clinical depression, subsyndromal depression and brief depressive episode across 43 low- and middle-income countries (LMICs). Method Cross-sectional, community-based data on 190 593 individuals from 43 LMICs recruited via the World Health Survey were analysed. Multivariable logistic regression analysis was done to assess the association between depression and physical multimorbidity. Results Overall, two, three and four or more physical health conditions were present in 7.4, 2.4 and 0.9% of non-depressive individuals compared with 17.7, 9.1 and 4.9% among people with any depressive episode, respectively. Compared with those with no depression, subsyndromal depression, brief depressive episode and depressive episode were significantly associated with 2.62, 2.14 and 3.44 times higher odds for multimorbidity, respectively. A significant positive association between multimorbidity and any depression was observed across 42 of the 43 countries, with particularly high odds ratios (ORs) in China (OR 8.84), Laos (OR 5.08), Ethiopia (OR 4.99), the Philippines (OR 4.81) and Malaysia (OR 4.58). The pooled OR for multimorbidity and depression estimated by meta-analysis across 43 countries was 3.26 (95% confident interval 2.98–3.57). Conclusions Our large multinational study demonstrates that physical health multimorbidity is increased across the depression spectrum. Public health interventions are required to address this global health problem.en_US
dc.language.isoenen_US
dc.publisherCambridge University Pressen_US
dc.subjectDepressionen_US
dc.subjectLow- and middle-income countriesen_US
dc.subjectMultimorbidityen_US
dc.subjectPhysical healthen_US
dc.subjectPsychiatryen_US
dc.titleDepression and physical health multimorbidity: primary data and country-wide meta-analysis of population data from 190 593 people across 43 low- and middle-income countriesen_US
dc.typeArticleen_US


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